Traveling to Southeast Asia in late 2025? Be aware of key infectious disease risks like dengue, COVID-19 variants, malaria, and more. Learn prevention tips and recommended vaccines.

Essential Infectious Disease Checklist Before Traveling to Southeast Asia (Second Half of 2025)

Table of Contents

• Dengue Fever
• COVID-19 (2025 variants)
• Malaria
• Hand, Foot, and Mouth Disease (HFMD)
• Avian Influenza (H5N1)
• Typhoid Fever
• Hepatitis A & B
• General Prevention Tips
• Frequently Asked Questions (FAQ)

1. Dengue Fever

Dengue fever continues to be one of the most prevalent mosquito-borne illnesses in Southeast Asia, especially during and after the rainy season (May–October). The virus is transmitted by Aedes mosquitoes and causes high fever, joint pain, rash, and, in severe cases, hemorrhagic symptoms. Countries like Thailand, Indonesia, and the Philippines have seen recent surges in 2025. There is currently no specific treatment or widely available vaccine, so prevention through mosquito bite avoidance is key.

2. COVID-19 (2025 variants)

While the global COVID-19 emergency is officially over, several new variants such as NB.1.8.1 and XEC have been reported in Thailand, Vietnam, and Malaysia. These variants are highly transmissible but generally milder. Travelers should stay updated on local policies, consider booster shots if in a high-risk group, and still practice respiratory hygiene in crowded or enclosed spaces.

3. Malaria

Although largely controlled in urban areas, malaria remains a threat in rural and forested regions of Myanmar, Cambodia, and Laos. Caused by Plasmodium parasites and transmitted through Anopheles mosquitoes, malaria can lead to severe illness and death if untreated. Prophylactic medications are recommended for travelers going to high-risk zones.

4. Hand, Foot, and Mouth Disease (HFMD)

HFMD is common among children and has seen seasonal outbreaks in countries like Singapore and Malaysia. It spreads via respiratory droplets and surfaces, and symptoms include fever, mouth sores, and rash on hands and feet. Although mild in most cases, it can disrupt travel plans for families. Regular handwashing and hygiene are essential.

5. Avian Influenza (H5N1)

H5N1 avian influenza remains under surveillance in several parts of Southeast Asia, particularly in regions with live poultry markets. Human transmission is rare but possible through direct contact with infected birds. Travelers are advised to avoid wet markets and undercooked poultry dishes in affected areas.

6. Typhoid Fever

Typhoid is a waterborne disease spread through contaminated food or water. Outbreaks are more common during the rainy season due to poor sanitation. Countries like Indonesia and Vietnam have reported periodic surges. A typhoid vaccine is recommended for long-term travelers and backpackers who may eat street food or travel to rural areas.

7. Hepatitis A & B

Hepatitis A is commonly transmitted through contaminated food and water, while Hepatitis B spreads via blood or bodily fluids. Both are vaccine-preventable. Ensure that your vaccinations are up to date, especially if you plan on extended stays or working in healthcare or educational settings abroad.

8. General Prevention Tips

• Check CDC or WHO travel advisories before your trip
• Carry mosquito repellent and wear long sleeves and pants
• Drink only bottled or properly filtered water
• Avoid raw seafood or uncooked street food
• Wash hands frequently with soap or alcohol-based sanitizer
• Consider travel insurance that covers infectious diseases

9. Frequently Asked Questions (FAQ)

Q1. Is it safe to travel to Southeast Asia in 2025?
Yes, with precautions. Most destinations are open and safe for travel, but staying informed and vaccinated is key.

Q2. Should I get any vaccines before traveling?
Yes. Hepatitis A and B, typhoid, and updated COVID-19 boosters are commonly recommended. Check with your doctor.

Q3. Can I catch dengue or malaria in cities?
Dengue is possible even in cities; malaria is more common in rural/forest areas. Prevention is important in both cases.

Q4. What happens if I get sick during my trip?
Most countries have good healthcare, especially in cities. Have travel insurance and know the local emergency numbers.

Q5. How can I track outbreaks while traveling?
Use CDC, WHO, or local health ministry websites. Some embassies also issue updates for citizens abroad.